Benjamin Winkeljann

Company: RNhale GmbH & LMU Munich

Job title: Group Leader

Seminars:

Workshop B: Advancing Drug Conjugates for RNAi Therapies: Optimizing the Design & Chemistry of Conjugates & Their Linkers for More Successful Development of RNAi Therapies 1:00 pm

Drug conjugates are being widely explored for their use with siRNAs and microRNAs. However, to successfully build these therapeutics, it is vital to understand the chemistry linking these components. Moreover, conjugated drug products have shown great potential in successful and efficient delivery. This workshop will gather experts to discuss: • How to design successful linkers…Read more

day: Pre-Conference Day

Expert Panel Discussion: Reviewing Production Strategies for New Delivery Platforms to Optimize Manufacturability to Enable Scale Up for the Clinic 2:00 pm

• Are peptide conjugates easier to produce on a larger scale compared to antibody conjugates? • How to ensure quality is maintained through the process? • How is the process being kept cost efficient?Read more

day: Conference Day Two

Dry Powder Formulations for Pioneering Local siRNA Delivery to the Lung 1:30 pm

• Nano-Embedded Microparticles (NEMs) offer a breakthrough in inhalable RNA therapeutics, ensuring optimal lung- delivery and enhanced compliance. • Adopting a cost-effective, scalable, and continuous spray-drying technique ensures particles optimized for deep lung delivery. • RNAi-based dry powder treatment against type 2 asthmatic disease demonstrates remarkable efficacy without any toxic effects in vivo.Read more

day: Conference Day Two