Workshop B: Advancing Drug Conjugates for RNAi Therapies: Optimizing the Design & Chemistry of Conjugates & Their Linkers for More Successful Development of RNAi Therapies
Time: 1:00 pm
day: Pre-Conference Day
Details:
Drug conjugates are being widely explored for their use with siRNAs and microRNAs. However, to successfully build these therapeutics, it is vital to understand the chemistry linking these components. Moreover, conjugated drug products have shown great potential in successful and efficient delivery.
This workshop will gather experts to discuss:
• How to design successful linkers between conjugates and siRNA/microRNA?
• Understanding the linker chemistry to ensure it is commercially manufacturable but still breaks apart at the correct point in the body.
• How are these new conjugate designs passing through the cell membrane?
• How do you ensure successful delivery to the target using conjugates, such as antibodies and peptides?
• Which kinds of conjugates should the field be prioritizing?
