Julia Alterman

Company: University of Massachusetts Medical School

Job title: Assistant Professor

Seminars:

Dissecting the Impact of Chemistry & Structure on siRNA Activity in the CNS 1:30 pm

Impact of phosphorothioate backbone modifications on siRNA accumulation and distribution in mice and sheep brains Impact of linker chemistry on siRNA accumulation and distribution in the mouse brain Dual targeting, multivalent siRNAs exhibit robust silencing of two genes in mouse brainRead more

day: Pre-Conference Day

Panel Discussion – Mapping Out the Landscape of Delivery Modalities 9:00 am

What are the pros and cons of current delivery modalities? Comparing peptides, polymers, antibodies, exosomes, and aptamers as delivery vehicles What is understood about their safety and efficacy? How validated are they for each cell type? How to improve the efficiency of delivery to the liver? Comparing the duration of effect across delivery mechanisms Comparing…Read more

day: Pre-Conference Day