Job title: Principal Scientist of Chemistry
Jimmy Weterings is Principal Scientist in the Discovery Sciences – Oligonucleotide chemistry team at AstraZeneca..
Jimmy has had a tight bond with oligonucleotides since 2002, performing research on PNA in the van Boom group at Leiden University and targeted ASO conjugates at Prosensa. During his Ph.D at Leiden University he synthesised and studied CpG and other TLR ligand containing conjugates. At Cenix BioScience, he developed targeted siRNA conjugates for CNS delivery. And at Cristal Therapeutics he lead various projects on the nanomedicine delivery of oligonucleotide in oncology. Recently he joined AstraZeneca, fully dedicating himself to the further advancement of (targeted) oligonucleotide therapeutics.
Jimmy (co-)authored 10 articles and holds several patents for drug delivery enabling technologies, including the most recent one on TMTHSI, a promising new conjugation compound for oligonucleotide and antibody conjugates.
Oligonucleotide Conjugation for Therapeutic Applications 11:20 am
Oligonucleotide conjugation strategies Biological impact of conjugation strategy Oligonucleotide conjugation opportunitiesRead more