Eriks Rozners

Company: Binghamton University Research Foundation

Job title: Professor

Seminars:

Amide-Modified RNA: Using Protein Backbone to Improve Specificity of siRNAs 2:30 pm

Amides are excellent mimics of phosphate linkages in RNA and are well tolerated in the guide strand of siRNAs Amide modification at the 5’-end (position 1) of the passenger strand suppresses its undesired off-target activity Amide modification in the seed region of the guide strand suppresses undesired microRNA-like off-target activity UNPUBLISHED DATARead more

day: Conference Day One

Round Table Discussion: How Can We Design Better RNAi Payloads? Enhancing Stability & Maximizing Precision Targeting of RNAi Therapies through Chemical Modifications 3:30 pm

How can alternative siRNA structures alter therapeutic delivery, efficacy and stability How to employ nucleoside modifications to ligands to influence therapeutic stability What innovative biochemical strategies are providing scope to improve RNAi therapiesRead more

day: Conference Day One