Engineering Self-Assembling RNA NanoStructures for Improved Precision Delivery in RNAi Therapeutic Delivery
- Developing programmable RNA origami structures that self-assemble into precise nanocarriers enabling tissue-specific delivery with reduced off-target effects
- Incorporating conditional stability triggers that respond to cellular microenvironment cues for controlled payload release at disease sites
- Demonstrating encapsulation efficiency through optimized nanostructure design significantly improving therapeutic payload delivery