Deep Learning-based Design of Cell-targeting Ligands Enables Cellspecific, Functional siRNA Delivery in Multiple Extra-hepatic Tissues
Time: 5:00 pm
day: Conference Day One
Details:
- Receptor-mediated endocytosis drives cell tropism across RNA modalities
- Deep learning-based design of ligands targeting endocytosing receptors enables rapid in vivo testing of receptors for their capacity to mediate functional siRNA delivery
- This platform – Connexa – has led to the discovery of multiple receptors capable of mediating in vivo functional siRNA delivery in extrahepatic tissues
UNPUBLISHED DATA
