Thomas Michler

Thomas Michler

Company: Technical University of Munich

Job title: Group Leader

Seminars:

Development of a Combinatorial RNAi/Immunotherapy for Chronic Hepatitis B 4:30 pm

High levels of Hepatitis B virus (HBV) antigens inhibit virus specific immune responses and prevent viral clearance • We developed a combinatorial RNAi/vaccination therapy which by suppressing immunoinhibitory viral proteins allows therapeutic vaccination to induce curative antiviral T cell responses in mice • Dysfunctional virus-specific T cells in high-titer HBV carrier mice showed an exhausted…Read more

day: Day One

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