Guy Hermans

Company: Sapreme Technologies

Job title: CEO

Seminars:

Expert Panel Discussion: The Right Delivery for the Right Therapeutic Area 9:30 am

The major challenge to harnessing RNAi for the treatment of disease is delivery of functional nucleic acid to the target tissues, cells, and subcellular compartments. This panel will discuss challenges and solutions they have found in their specific areas of interest.Read more

day: Conference Day Two

Unprecedented, Tissue- & Modality-Agnostic Potency & Durability Improvement by Targeted Endosomal Escape In Vitro & In Vivo: an Update on Sapreme’s Unique Endosomal Escape Enhancer Platform 12:00 pm

• Efficient intracellular delivery of oligonucleotides remains a bottleneck in hepatic and especially extrahepatic tissues • Sapreme’s endosomal escape enhancers allow for highly efficient and tissue specific intracellular delivery, using existing targeting ligands and payloads • We will share data demonstrating in vivo liver, muscle and solid tumor delivery of oligonucleotides, allowing strong dose reductions…Read more

day: Conference Day Two