DegradaBALL-siRNA Complex (LEM-S401) for Effective Local Administration to Treat Skin Fibrosis

Time: 4:00 pm
day: Track B Day 1 PM


  • New concept of DDS, DegradaBALL, was employed for siRNA therapeutics against skin fibrosis (LEM-S401)
  • Local injection of LEM-S401 showed highly effective and sustainable knockdown efficiency at the injection site
  • Local injection of the DegradaBALL-RNA complex would be well-suited for extrahepatic delivery by minimizing liver accumulation